We are part of the Department of Biomedical and Molecular Sciences at Queen’s University in Kingston, Canada.
We focus on positive-sense RNA viruses, a large group of important human viruses that include hepatitis C virus (HCV), West Nile virus, dengue virus, SARS coronaviruses, norovirus (“stomach flu”) and rhinovirus (the common cold virus). We aim to characterize and therapeutically exploit early stages of positive-sense RNA virus infection, including entry and virus-induced remodelling of intracellular membranes to form replication organelles (“viral forts”) within infected cells. Our goal is to identify broadly acting antiviral strategies through targeting conserved aspects of positive-sense RNA virus infection, ultimately leading to the development of broad-spectrum antivirals against this group of viruses. Please see our research page for more details about the specific areas of research in our lab!
We are always interested in hearing from enthusiastic students – if this sounds interesting, or you’d like to learn more, please get in touch!