Publications

  1. Olbrich A, Wardemann J, Böhm S, Rother K, Colpitts CC, Wrensch F, Baumert TF, Berg T and Beckert J. (2019) Repertoire and neutralizing activity of antibodies against E2 peptide in patients with spontaneous resolution of hepatitis CJ. Infect. Dis. doi: 10.1093/infdis/jiz274.
  2. Colpitts CC, Tawar RG, Mailly L, Thumann C, Heydmann L, Durand SC, Xiao F, Pessaux P, Zeisel MB and Baumert TF (2018) Humanisation of a claudin-1-specific monoclonal antibody for clinical prevention and cure of HCV infection without escapeGut doi: 10.1136/gutjnl-2016-312577
  3. Eller C, Heydmann L, Colpitts CC, Verrier ER, Schuster C and Baumert TF (2018) The functional role of sodium taurocholate cotransporting polypeptide NTCP in the life cycle of hepatitis B, C and D virusesCell. Mol. Life Sci.71:3895-3905
  4. Behrendt P, Perin P, Menzel N, Banda D, Pfaender S, Alves MP, Thiel V, Meulemann P, Colpitts CC, Schang LM, Vondran FWR, Kusuma A, Manns MP, Steinmann E and Pietschmann T (2017) Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entryAntiviral Res. 147:19-28 
  5. Colpitts CC and Baumert TF (2017) SMAD about hepatitis C virus cell entry and liver diseaseGastroenterology 152:21-23 
  6. Colpitts CC and Baumert TF (2017) SCARB1 variants and HCV infection: Host susceptibility is lost in translationJ. Hepatol. doi: 10.1016/j.jhep.2017.04.013 
  7. Colpitts CC, Chung RT and Baumert TF (2017) Entry inhibitors: A perspective for prevention of hepatitis C virus infection in liver transplantationACS Infect. Dis. 3:620-623 
  8. Colpitts CC and Baumert TF (2017) Claudins in viral infection: From entry to spreadPflugers Arch. 469:27-34
  9. Verrier ER#, Colpitts CC#, Bach C, Heydmann L, Zona L, Xiao F, Thumann C, Crouchet E, Gaudin R, Sureau C, Cosset FL, McKeating JA, Pessaux P, Hoshida Y, Schuster C, Zeisel MB and Baumert TF (2016) Solute carrier NTCP regulates innate antiviral immune responses targeting hepatitis C virus infection of hepatocytesCell Reports 17:1357-1368 (#equal contribution)
  10. Verrier ER, Colpitts CC, Bach C, Heydmann L, Weiss A, Renaud M, Durand SC, Habersetzer F, Durantel D, Abou-Jaoudé G, López Ledesma MM, Felmlee DJ, Soumillon M, Croonenborghs T, Pochet N, Nassal M, Schuster C, Brino L, Sureau C, Zeisel MB and Baumert TF (2016) A targeted functional RNAi screen uncovers glypican 5 as an entry factor for hepatitis B and D virusesHepatology 63:35-48 
  11. Colpitts CC and Baumert TF (2016) Cell surface glycans as viral entry factors and antiviral targets. Chapter published in Recent Progress in Glycotherapy Book by Bentham Science 
  12. Verrier ER, Colpitts CC, Schuster C, Zeisel MB and Baumert TF (2016) Cell culture models for the investigation of hepatitis B and D virus infectionViruses 8pii: E261
  13. Colpitts CC, Lupberger J and Baumert TF (2016) Multifaceted role of E-cadherin in hepatitis C virus infection and pathogenesis. Proc. Natl. Acad. Sci. USA 113:7298-300 
  14. Colpitts CC and Baumert TF (2016) Addressing the challenges of hepatitis C virus resistance and treatment failureViruses doi: 10 3390/v8080226 
  15. Fauvelle C, Colpitts CC, Keck Z, Pierce BG, Foung SKH and Baumert TF (2016) Hepatitis C virus B cell vaccines inducing protective neutralizing antibodiesExpert Rev. Vaccines doi:10 1080/14760584 2016 1194759 
  16. Colpitts CC and Baumert TF (2016) Hepatitis C virus cell entry: A target for novel antiviral strategies to address limitations of direct acting antiviralsHepatol. Int.10: 741-48 
  17. Verrier ER, Colpitts CC, Sureau C and Baumert TF (2016) Hepatitis B virus receptors and molecular drug targetsHepatol. Int. 10:567-73 
  18. Tawar RG, Colpitts CC, Timm J, Fehm T, Roggendorf M, Meisel H, Meyer N, Habersetzer F, Cosset FL, Berg T, Zeisel MB and Baumert TF (2015) Acute hepatitis C virus infection induces anti-host cell receptor antibodies with virus-neutralizing propertiesHepatology 62:726-36 
  19. Kusuma A, Romero-Brey I, Berger C, Colpitts CC, Boldanova T, Engelmann M, Todt D, Perin PM, Behrendt P, Vondran FW, Xu S, Goffinet C, Schang LM, Heim MH, Bartenschlager R, Pietschmann T and Steinmann E (2015) Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication via blockage of membranous web formationHepatology 62:702-14 
  20. Colpitts CCand Baumert TF (2015) A new HCV cell culture model for the next clinical challengesNat. Rev. Gastro. Hepatol. 12:611-13 
  21. Colpitts CC, El-Saghire H, Pochet N, Schuster C and Baumert TF (2015) High-throughput approaches to unravel hepatitis C virus-host interactionsVirus Res. 218: 18-24
  22. Colpitts CC, Verrier ER and Baumert TF (2015) Targeting viral entry for treatment of hepatitis B and C virus infectionsACS Infect. Dis. 1:420-427 
  23. Colpitts CC, Lupberger J, Doerig C and Baumert TF (2015) Host cell kinases and the hepatitis C virus life cycleBiochim. Biophys. Acta Proteins Proteom. 1854:1657-62 
  24. Colpitts CC, Zeisel MB and Baumert TF (2015) When one receptor closes, another opens: Claudins and the hepatitis C virus E1 glycoproteinHepatology 62:991-3 
  25. Tawar RG, Colpitts CC, El-Saghire H, Lupberger J, Zeisel MB and Baumert TF (2015) Claudins and pathogenesis of viral infectionSem. Cell. Dev. Biol. 42:39-46 
  26. Colpitts CC and Schang LM (2014) A small molecule inhibits virion attachment to heparan sulfate- or sialic acid-containing glycansJ. Virol. 88:7806-17 
  27. Kusuma A, Colpitts CC, Schang LM, Rachmawati H, Frentzen A, Pfaender S, Behrendt P, Brown RJP, Bankwitz D, Steinmann J, Ott M, Meuleman P, Rice CM, Ploss A, Pietschmann T and Steinmann E (2014) Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cellsGut 63:1137-49
  28. Colpitts CC, Ustinov AV, Epand RF, Epand RM, Korshun VA and Schang LM (2013) 5-(Perylen-3-yl)ethynyl-arabino-uridine (aUY11), an arabino-based rigid amphipathic fusion inhibitor, targets virion envelope lipids to inhibit fusion of influenza, hepatitis C and other enveloped virusesJ. Virol. 87(7): 3640-54
  29. Kim SY, Colpitts CC, Wiedemann G, Jepson C, Rahimi M, Rothwell JR, McInnes AD, Hasebe M, Reski R, Sterenberg BT and Suh D-Y (2013) Physcomitrella PpORS, basal to plant type III polyketide synthases in phylogenetic trees, is a very long chain 2-oxoalkylresorcinol synthaseJ. Biol. Chem. 288: 2767-77 
  30. Ciesek S, von Hahn T, Colpitts CC, Schang LM, Friesland M, Steinmann J, Manns MP, Ott M, Wedermeyer H, Meuleman P, Pietschmann T and Steinmann E (2011) The green tea polyphenol epigallocatechin-3-gallate (EGCG) inhibits hepatitis C virus (HCV) entry. Hepatology 54:1947-55
  31. Colpitts CC, KimSS, Posehn SE, Jepson C, Kim SY, Weidemann G, Reski R, Wee AGH, Douglas CJ and Suh D-Y (2011) PpASCL, a moss homolog of anther-specific chalcone synthase-like enzymes, is a hydroxyalkylpyrone synthase involved in an evolutionarily conserved sporopollenin biosynthesis pathwayNew Phytol. 192:855-68
  32. St Vincent MR, Colpitts CC, Ustinov AV, Muqadas M, Joyce MA, Barsby NL, Epand RF, Epand RM, Khramyshev SA, Valueva OA, Korshun VA, Tyrrell DLJ and Schang LM (2010) Rigid amphipathic fusion inhibitors, small molecule antiviral compounds against enveloped virusesProc. Natl. Acad. Sci. USA 107:17339-44
  33. Kim SS, Grienenberger E, Lallemand B, Colpitts CC, Kim SY, Geoffroy P, Heintz D, Krahn D, Kaiser M, Kombrink E, Heitz T, Suh D-Y, Legrand M and Douglas CJ (2010Polyketide synthase A and polyketide synthase B encode hydroxyalkyl α-pyrone synthases required for pollen development and sporopollenin biosynthesis in Arabidopsis thalianaPlant Cell 22: 4045-66
  34. Koduri PK, Gordon GS, Barker EI, Colpitts CC, Ashton NW and Suh D-Y (2010) Genome-wide analysis of the chalcone synthase superfamily genes of Physcomitrella patens. Plant Mol. Biol. 72: 247-63